MicroRNA

Source: Baylor College of Medicine Summary: Disturbing the normal function of microRNAs can lead to altered expression of their target genes, and this has been associated with a wide variety of human diseases, such as cancer, cardiovascular and developmental diseases.   More Information: Ninad Oak et al, “Framework for microRNA variantRead More →

reprogrammed stem cells regenerate lost muscle mass in muscular dystrophy.

Source: Northwestern University Summary: In a new study, researchers have reprogrammed stem cells and demonstrated the potential to regenerate lost muscle mass in muscular dystrophy. Muscular dystrophy is a group of inherited muscle diseases characterized by the progressive loss of both skeletal and cardiac muscle mass. The most common type muscular dystrophies include Duchenne muscular dystrophy, BeckerRead More →

Type 1 diabetes treated through gene therapy

Source: Boston Children’s Hospital Summary: Researchers have successfully reversed Type 1 Diabetes in a mouse model by infusing modified blood stem cells pre-treated to produce a protein which is deficient in Type 1 diabetic mice (and people). In type 1 diabetes (T1D), autoreactive T-cells of the immune system attack islet cellsRead More →