Tracking Down MicroRNA Candidates That Can Contribute to Disease


Source: Baylor College of Medicine

Summary: Disturbing the normal function of microRNAs can lead to altered expression of their target genes, and this has been associated with a wide variety of human diseases, such as cancer, cardiovascular and developmental diseases.


 

MicroRNA

MicroRNA and mRNA visualization in differentiating C1C12 cells. Credit: Ryan Jeffs/Wikipedia


More Information: Ninad Oak et al, “Framework for microRNA variant annotation and prioritization using human population and disease datasets”, Human Mutation (2018). DOI: 10.1002/humu.23668


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