Scientists Identify Body’s Microreactors For Innate Immunity


Source: UT Southwestern Medical Center

Summary: Researchers reported that a DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body’s first response to infection.


in-born immunity system

(l-r) Mingjian Du and Dr. Zhijian “James” Chen. Credit: UT Southwestern


More Information: Mingjian Du et al, “DNA-induced liquid phase condensation of cGAS activates innate immune signaling”, Science (2018). DOI: 10.1126/science.aat1022


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