Scientists Find That Sensory Neurons Can be Used to Discover Therapies for ALS

Source: Virginia Tech

Summary: Scientists have shown that mutations in specific genes that destroy motor neurons and thereby cause the devastating effects of amyotrophic lateral sclerosis also known as ALS or Lou Gehrig’s disease also attack sensory neurons.


Virginia Tech Carilion Research Institute scientists led by associate professor Gregorio Valdez (center) study sensory neurons to provide new mechanistic insights to prevent, slow, or even reverse ALS. Credit: Clayton Metz/Virginia Tech

More Information: Sydney K. Vaughan et al. The ALS-inducing factors, TDP43A315T and SOD1G93A, directly affect and sensitize sensory neurons to stress, Scientific Reports (2018). DOI: 10.1038/s41598-018-34510-8

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