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Scientists Accidentally Reprogram Mature Mouse GABA Neurons into Dopaminergic-like Neurons

Scientists Accidentally Reprogram Mature Mouse GABA Neurons into Dopaminergic-like Neurons


Source: Cell Press

Summary: Attempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells.


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Dr. Chun-Li Zhang and Lei-Lei Wang. Credit: David Gresham / UT Southwestern

More Information: Stem Cell Reports, Zhang et al, “Phenotypic reprogramming of striatal neurons into dopaminergic neuron-like cells in the adult mouse brain”, Stem Cell Reports (2018) DOI: 10.1016/j.stemcr.2018.09.004


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