Macular Degeneration Linked to Aging Immune Cells
Source: Washington University School of Medicine
Summary: A new research study suggests that aging immune cells increase the risk for age-related macular degeneration, a major cause of blindness in the U.S.
Prof. Rajendra S. Apte said, “It’s possible to envision immune-based therapies that would tweak the level of microRNAs so that these macrophage cells no longer contribute to disease”, “Such therapies are a long way off, and we need to do a lot more research, but if we could make these older cells more like the younger ones, we might be able to prevent a great deal of vision loss.”
More Information: Lin JB et al, “Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration”, JCI Insight (2018). doi.org/10.1172/jci.insight.120157