Enzyme Blocker Stops Growth of Deadly Brain Tumor

Source: Northwestern University

Summary: Researchers were able to halt the growth of glioblastoma, an aggressive form of brain cancer, by inhibiting an enzyme called CDK5, according to a new study.

Tumor cells

Glioblastoma cells (orange) spread throughout a fly brain (normal cells in blue), used to model human cancer. Credit: Northwestern University

More Information: CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells. Cell Reports. DOI: doi.org/10.1016/j.celrep.2018.04.016

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