Brain

Source: Virginia Tech Summary: Scientists have shown that mutations in specific genes that destroy motor neurons and thereby cause the devastating effects of amyotrophic lateral sclerosis also known as ALS or Lou Gehrig’s disease also attack sensory neurons. More Information: Sydney K. Vaughan et al. The ALS-inducing factors, TDP43A315T and SOD1G93A,Read More →

Zebra fish

Source: University of Edinburgh. Summary: Fresh insights into how zebrafish repair their damaged nerve connections could aid the development of therapies for people with spinal cord injuries. More Information: Themistoklis M. Tsarouchas et al, Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration, Nature Communications (2018). DOI: 10.1038/s41467-018-07036-wRead More →

MicroRNA

Source: Baylor College of Medicine Summary: Disturbing the normal function of microRNAs can lead to altered expression of their target genes, and this has been associated with a wide variety of human diseases, such as cancer, cardiovascular and developmental diseases.   More Information: Ninad Oak et al, “Framework for microRNA variantRead More →

Online programme

Source: University of Illinois at Chicago Summary: Although up to 20% of adolescents experience a depressive episode each year, the medical community has struggled to implement programs that effectively prevent depression. Researchers have worked to fill this gap in pediatric primary care by conducting clinical trials to evaluate and compare interventions. More Information: JAMA NetworkRead More →

Positive Creativity

Source: University of Oregon Summary: According to new research, children who create imaginary parallel worlds, alone or with friends, are more found more commonly than previously believed. In a project designed to probe the dynamics of behavior among children 8-12 years old, researchers found that about 17% of them, inRead More →

Gene PPM1D

Source: Baylor College of Medicine Summary: In this study, researchers combined clinical and laboratory studies to show that a gene called PPM1D, whose function in blood production was unknown, can confer blood cells exposed to the chemotherapy agent cisplatin a survival advantage that might favor the development of leukemia yearsRead More →

Circadian Rhythm

Source: Science X Network Summary: A team of researchers affiliated with several institutions in the U.S. has identified circadian rhythm patterns in human skin based on genetic biomarkers. More Information: Gang Wu et al. Population-level rhythms in human skin with implications for circadian medicine, Proceedings of the National Academy of Sciences (2018).Read More →

Cytokines

Source: UT Southwestern University Summary: Researchers at have identified blood-based biomarkers that may help identify those patients at greatest risk of developing autoimmune side effects from the treatment.   More Information: Shaheen Khan et al, “Immune dysregulation in cancer patients developing immune-related adverse events”, British Journal of Cancer (2018). DOI: 10.1038/s41416-018-0155-1 Read More →

Genetic disease

Source: McGill University Health Centre Summary: An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response. Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapyRead More →

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